People with thalassemia have a genetic defect of their red blood cells that affects the cells' ability to produce normal hemoglobin. Red blood cells use hemoglobin to carry oxygen to tissues. As a result of the defect, most forms of thalassemia produce a chronic, lifelong anemia that begins in early childhood, and often must be treated with frequent transfusions.

Causes

Thalassemia is a group of genetic blood disorders that affect approximately 1,000 individuals in the United States. The most severe of these disorders is Cooley's Anemia.

Risk Factors

Thalassemia in the family or other blood clotting disorders.

Symptoms

Excessive bleeding and wounds taking a long time to heal or clot.

Treatment

Treated with frequent transfusions.

Resources

Cooley's Anemia Foundation (http://www.thalassemia.org)

References:

CDC