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Disease Information, Treatments and Possible Cures
Hepatitis D virus (HDV)

Hepatitis D is a liver disease caused by the hepatitis D virus (HDV), a defective virus that needs the hepatitis B virus to exist. Hepatitis D virus (HDV) is found in the blood of persons infected with the virus.

Cause

Hepatitis D virus (HDV)

Risk Factors

  • Injection drug users
  • Men who have sex with men
  • Hemodialysis patients
  • Sex contacts of infected persons
  • Health care and public safety workers
  • Infants born to infected mothers
    (very rare)

    Symptoms

    • jaundice
    • fatigue
    • abdominal pain
    • loss of appetite
    • nausea, vomiting
    • joint pain
    • dark (tea colored) urine
  • HDV can be acquired either as
    • a co-infection (occurs simultaneously) with hepatitis B virus (HBV) or
    • as a superinfection in persons with existing chronic HBV infection.
  • HBV-HDV co-infection:
    • may have more severe acute disease and a higher risk (2%-20%) of developing acute liver failure compared with those infected with HBV alone
  • HBV-HDV superinfection
    • chronic HBV carriers who acquire HDV superinfection usually develop chronic HDV infection
      • progression to cirrhosis is believed to be more common with HBV/HDV chronic infections

    Diagnosis

    See your medical practioner.

    Treatment

  • Acute HDV infection
    • Supportive care
  • Chronic HDV infection
    • interferon-alfa
    • liver transplant

    Prevention

    Avoid the risk factors

    References

    CDC

  • .


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