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Disease Information, Treatments and Possible Cures
Ascariasis (Roundworm)

Ascariasis is an intestinal worm infestation present worldwide, though mostly in tropical climates.

Ascaris lumbricoides is a nematode (round worm) parasite that can reach up to 40 cm in length. As with most parasites, Ascaris have a complex life cycle that begins with ingesting their eggs. After hatching in the gut, immature forms of the parasite travel to the heart and lungs, causing a type of pneumonia. They then migrate into the throat where they are swallowed, enter the gut again, and develop into adult worms. The eggs they lay (240,000 per worm per day) pass out with feces, to begin their cycle again when contaminated food or water is ingested.

How common is ascariasis?

Ascariasis is the most common human worm infection. Infection occurs worldwide and is most common in tropical and subtropical areas where sanitation and hygiene are poor. Children are infected more often than adults. In the United States, infection is rare, but most common in rural areas of the southeast.

Causes

  • Ingesting food or water contaminated by feces containing eggs

Risk Factors

The following factors increase your chances of developing ascariasis:

  • Preschool age or younger

  • Travel to developing countries

  • Living in southern states of the US

  • Eating unsanitary food

  • Drinking unclean water

Symptoms

If you experience any of these symptoms do not assume it is due to ascariasis. These symptoms may be caused by other health conditions. If you experience any one of them, and have been exposed to risks, see your physician.

  • Pneumonia (dry cough and fever)

  • Wheezing

  • Abdominal cramps

  • Vomiting

  • Malnutrition, especially in children

  • Passing a worm either by mouth, nose, or rectum

  • Diseases caused by Ascaris

    • Gallbladder disease

    • Liver abscess

    • Pancreatitis

    • Appendicitis

    • Peritonitis

How is an Ascaris infection spread?

Ascaris eggs are found in human feces. After feces contaminates the soil, the eggs become infectious after a few weeks. Infection occurs when a person accidentally ingests (swallows) infectious Ascaris eggs. Once in the stomach, immature worms hatch from the eggs. The larvae are carried through the lungs and then to the throat where they are swallowed. Once swallowed, they reach the intestines and develop into adult worms. Adult female worms lay eggs that are then passed in feces; this cycle will take between 2-3 months.

Pigs can be infected with another species of Ascaris. Occasionally, a pig Ascaris infection can be spread to humans; this occurs when infective eggs, found in the soil and manure, are ingested. Infection is more likely if pig feces is used as fertilizer in the garden; crops then become contaminated with Ascaris eggs.

How can I get ascariasis?

You or your children can become infected after touching your mouth with your hands that have become contaminated with eggs from soil or other contaminated surfaces or by ingesting contaminated food or water.

What should I do if I think I have ascariasis?

See your health care provider.

Diagnosis

Your doctor will ask about your symptoms, travel and medical history, and perform a physical exam. You may be referred to a gastroenterologist or a specialist in tropical diseases. Tests may include the following:

  • Blood and urine tests

  • Stool specimens to search for worm eggs

  • Intestinal x-rays or ultrasound imaging

Treatment

It is common to have more than one intestinal parasite. You may need to be treated for several. Talk with your doctor about the best treatment plan for you. Treatment options include the following:

  • Drugs – Mebendazole, albendazole, and pyrantel pamoate are all effective medications that kill Ascariasis.

  • Endoscopy or surgery – Intestinal obstruction from a large number of worms may require further intervention.

Prevention

To help reduce your chances of getting ascariasis, take the following steps:

  • Avoid contacting soil that may be contaminated with human feces.

  • Do not defecate outdoors.

  • Dispose of diapers properly.

  • Wash hands with soap and water before handling food.

  • When traveling to countries where sanitation and hygiene are poor, avoid water or food that may be contaminated.

  • Wash, peel or cook all raw vegetables and fruits before eating.

Should I be concerned about spreading infection to the rest of my household?

No. Infection is not spread from person to person.

RESOURCES:

Center for Disease Control (CDC)
http://www.cdc.gov

The Nemours Foundation
http://kidshealth.org

World Health Organization
http://www.who.int

CANADIAN RESOURCES:

Communicable Disease Control (CDC) Unit
Manitoba Health, Public Health Branch
http://www.gov.mb.ca/health/publichealth/cdc/index.html

References:

Ascariasis. DynaMed website. Available at: http://www.dynamicmedical.com/dynamed.nsf?opendatabase. Accessed October 4, 2005.

Beers MH, Berkow R. The Merck Manual, 17th ed. West Point, PA: Merck & Co;1999.

Weller PF, Nutman TB. Intestinal nematodes. In: Kasper DL et al., eds. Harrison's Principles of Internal Medicine, 16th ed. New York: McGraw-Hill; 2005:1256-1257.

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