Aluminum toxicity occurs when a person breathes in high levels of aluminum from the air, or stores high levels of aluminum in his or her body.
Aluminum is the most abundant metal in the earth’s crust, and is present in the environment combined with other elements (eg, oxygen, silicon, fluorine). Exposure to aluminum is usually not harmful, but exposure to high levels can cause serious health problems. If you suspect you have been exposed to high levels of aluminum, contact your doctor.
Causes
Because aluminum is found in virtually all food, water, air, and soil, people may be exposed to high levels of aluminum when they:
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Eat foods containing high levels of aluminum
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Breath aluminum dust in workplace air
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Live in dusty environments
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Live where aluminum is mined or processed
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Live near certain hazardous waste sites
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Live where aluminum is naturally high
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Receive vaccinations containing aluminum
Risk Factors
Anyone can develop this condition, but certain people are more likely to develop aluminum toxicity. The following factors increase your chances of developing aluminum toxicity. If you have either of these risk factors, tell your doctor:
Symptoms
If you experience any of these symptoms, do not assume it is because of aluminum toxicity. These symptoms may be caused by other, less serious health conditions. If you experience any one of them, see your physician, especially if you have kidney disease or are on dialysis.
Diagnosis
Your doctor will ask about your symptoms and medical history, and perform a physical exam.
Tests may include the following:
Treatment
Talk with your doctor about the best treatment plan for you. Treatment options include:
Medications
The medication, deferoxamine mesylate, may be given to help eliminate aluminum from your body. This substance works through a procedure known as chelation, which assists in ridding the body of poisonous materials.
Aluminum Avoidance
Your doctor can instruct you on how to avoid exposure to aluminum from your diet and other sources.
Prevention
To help reduce your chances of getting aluminum toxicity, take steps to avoid the following, which may contain aluminum:
RESOURCES:
Agency for Toxic Substances and Disease Registry
http://www.atsdr.cdc.gov
Environmental Protection Agency
http://www.epa.gov
CANADIAN RESOURCES:
Environmental Health Association of Nova Scotia
http://www.lesstoxicguide.ca
Poison Control Centers for Canada
http://www.acpo.on.ca
References:
D’Haese PC, Couttenye MM, Goodman WG, Lemoniatou E, et al. Use of the low-dose desferrioxamine test to diagnose and differentiate between patients with aluminum-related bone disease, increased risk for aluminum toxicity, or aluminium overload. Nephrol dial Transplant. 1995;10:1874-84.
Kawahara M. Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases. J Alzheimers Dis. 2005;8:171-82.
Malluche HH. Aluminum and bone disease in chronic renal failure. Nephrol dial Transplant. 2002; 17:21-24.
Tox FAQs for aluminum. Agency for Toxic Substances and Disease Registry website. Available at: http://www.atsdr.cdc.gov/tfacts22.html. Accessed October 24, 2006.
Toxicity, aluminum. emedicine Web site. Available at: http://www.emedicine.com/med/topic113.htm. Accessed October 24, 2006.
