Michael Sinclair (born January 31, 1968 in Galveston, Texas) is a former American Football defensive end who played eleven seasons in the National Football League from 1992 to 2002 with the Seattle Seahawks and the Philadelphia Eagles.

Sinclair played college football at Eastern New Mexico University and was a three time Pro Bowler in 1996. 1997 and 1998 in which he led the NFL in sacks with 16.5 that season.